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Oxford Biomedica and PhoreMost enter gene therapy discovery collaboration

Oxford Biomedica and PhoreMost enter gene therapy discovery collaboration

Oxford Biomedica and PhoreMost enter gene therapy discovery collaboration to develop next-generation CAR-T cell therapies with improved efficacy and durability. PhoreMost’s SITESEEKER platform will identify active peptides to be deployed within Oxford Biomedica’s LentiVector® delivery system.

Oxford Biomedica, a leading gene and cell therapy group, and PhoreMost, the UK-based biopharmaceutical company dedicated to developing drugs against intractable disease targets, have announced that they have entered into a discovery collaboration to develop next-generation CAR-T cell therapies. Financial details of the agreement are not disclosed.

PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER®, to identify therapeutic candidates for Oxford Biomedica’s LentiVector® gene therapy delivery system. The programme will initially focus on CAR-T therapy and aims to develop next-generation cell therapies with significantly improved efficacy and durability.

John Dawson, CEO of Oxford Biomedica, said: "We are excited to apply this next-generation technology to our LentiVectorplatform. The collaboration has the potential to deliver more effective CAR-T therapies, and we look forward to working closely with the PhoreMost team."

Dr Chris Torrance, CEO, PhoreMost, said: "This collaboration with Oxford Biomedica, a global pioneer in cell and gene therapies, is further recognition of the power of SITESEEKER, offering an exciting opportunity to discover and accelerate the development of clinical-stage products. The natural complementarity between SITESEEKER and LentiVector offers great promise for this and future collaborations between the two companies."

Oxford Biomedica is a world-leading pioneer of cell and gene therapies. Its LentiVector® platform enables the successful development of breakthrough gene and cell-based medicines, and through collaborations with pharmaceutical partners, has delivered the first FDA and EMA approved CAR-T cell therapy.

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